翻訳と辞書
Words near each other
・ "O" Is for Outlaw
・ "O"-Jung.Ban.Hap.
・ "Ode-to-Napoleon" hexachord
・ "Oh Yeah!" Live
・ "Our Contemporary" regional art exhibition (Leningrad, 1975)
・ "P" Is for Peril
・ "Pimpernel" Smith
・ "Polish death camp" controversy
・ "Pro knigi" ("About books")
・ "Prosopa" Greek Television Awards
・ "Pussy Cats" Starring the Walkmen
・ "Q" Is for Quarry
・ "R" Is for Ricochet
・ "R" The King (2016 film)
・ "Rags" Ragland
・ ! (album)
・ ! (disambiguation)
・ !!
・ !!!
・ !!! (album)
・ !!Destroy-Oh-Boy!!
・ !Action Pact!
・ !Arriba! La Pachanga
・ !Hero
・ !Hero (album)
・ !Kung language
・ !Oka Tokat
・ !PAUS3
・ !T.O.O.H.!
・ !Women Art Revolution


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

cellular microarray : ウィキペディア英語版
cellular microarray
A cellular microarray is a laboratory tool that allows for the multiplex interrogation of living cells on the surface of a solid support. The support, sometimes called a "chip", is spotted with varying materials, such as antibodies, proteins, or lipids, which can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in phenotype, or detection of a response from the cell, such as a specific secreted factor.
There are a large number of types of cellular microarrays:
# Reverse transfection cell microarrays. David M. Sabatini's laboratory developed reverse-transfection cell microarrays at the Whitehead Institute, publishing their work in 2001.
# PMHC Cellular Microarrays. This type of microarray were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at Stanford University Medical Center.
==References==

*Chen DS, Davis MM (2006) Molecular and functional analysis using live cell microarrays. Curr Opin Chem Biol 10:28-34
*Chen DS, Soen Y, Stuge TB, Lee PP, Weber JS, Brown PO, Davis MM (2005) Marked Differences in Human Melanoma Antigen-Specific T Cell Responsiveness after Vaccination Using a Functional Microarray. PLoS Med 2: 10: e265 (http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371%2Fjournal.pmed.0020265)
*Soen Y., Chen D. S., Kraft D. L., Davis M. M. and Brown P.O. (2003) Detection and characterization of cellular immune responses using peptide-MHC microarrays. PLoS Biol. 1: E65 (http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0000065)
*Chen DS, Davis MM (2005) Cellular immunotherapy: Antigen recognition is just the beginning. Springer Semin Immunopathol 27:119–127
*Chen DS, Soen Y, Davis MM, Brown PO (2004) Functional and molecular profiling of heterogeneous tumor samples using a novel cellular microarray. J Clin Oncol 22:9507 (http://meeting.jco.org/cgi/content/abstract/22/14_suppl/9507)
*Soen Y, Chen DS, Stuge TB, Weber JS, Lee PP, et al. (2004) A novel cellular microarray identifies functional deficiences in tumor-specific T cell responses. J Clin Oncol 22:2510
*Ziauddin J, Sabatini DM (2001) Microarrays of cells expressing defined cDNAs. Nature. 2001 May 3;411(6833):107-10. (Pubmed link )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「cellular microarray」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.